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Cyberinfrastructure

US National Supercomputing & HPC

ACCESS (Advanced Cyberinfrastructure Coordination Ecosystem: Services & Support)

ACCESS - NSF-funded cyberinfrastructure ecosystem providing researchers with access to advanced computing resources

ACCESS Anvil - Purdue University's composable system with 84 H100 GPUs added for NAIRR initiatives

ACCESS Bridges-2 - Pittsburgh Supercomputing Center's heterogeneous architecture with extreme memory nodes

ACCESS Delta - NCSA's GPU-focused system, "most performant GPU resource in NSF portfolio" with 5.16 petaflops

ACCESS Expanse - San Diego Supercomputer Center's 5.16 petaflops system with Kubernetes subsystem

ACCESS Frontera - TACC's fastest US academic supercomputer, $60M NSF investment

Horizon Supercomputer - TACC's upcoming $457M system at LCCF, 10× Frontera performance expected 2026

Jetstream2 - NSF-funded cloud computing resource with 8 petaFLOPS for science and engineering research

International HPC & Supercomputers

ARCHER2 - UK's 28 PFLOP/s national supercomputing service

EuroHPC Joint Undertaking - European initiative with 11+ supercomputers including JUPITER exascale system

IDRIS Jean Zay - France's 125.9 PFLOPS AI-focused system with 1456 H100 GPUs (Jean Zay supercomputer)

Snellius - Netherlands national 14 petaflops supercomputer operated by SURF

Cloud & Distributed Infrastructure

Research Cloud Platforms

Chameleon Cloud - NSF-funded cloud research testbed, Phase 4 with $12M funding through 2028

CloudLab - NSF-funded cloud research infrastructure with 1000+ machines for experimental cloud computing

CloudBank - NSF-funded cloud access program, CloudBank 2.0 launched April 2025 with $20M

NIH STRIDES - NIH Strategic Partnerships providing AWS, Google, Azure access with enterprise support

Commercial Cloud Research Credits

AWS Cloud Credit for Research - Amazon Web Services research credit program

Google Cloud Research Credits - Google Cloud Platform credits for academic researchers

Microsoft Azure Research Credits - Azure credits for academic research projects

Commercial Cloud Education Programs

AWS Cloud for Education - Amazon educational programs and credits

Google Cloud for Education - Google Cloud education programs

Microsoft Azure for Education - Azure for students and educators

GitHub Education - GitHub student developer pack with free Codespaces hours

DigitalOcean - commercial cloud platform with education and research programs

Open Source Cloud Software

OpenStack - most widely deployed open source cloud software in the world, powers many research clouds

Federated Kubernetes & Distributed Computing

National Research Platform (NRP) - formerly Pacific Research Platform, multi-institutional deployment with 1400+ GPUs

2i2c - designs, develops, and operates JupyterHubs in the cloud for 90+ research & education communities (7000+ users)

High Throughput Computing

Open Science Grid (OSG) - consortium dedicated to distributed High Throughput Computing (dHTC) for open science

PATh (Partnership to Advance Throughput Computing) - $22.5M NSF project for throughput computing, includes OSG

Cloud Workbenches & Science Platforms

Multi-Domain Platforms

CyVerse Discovery Environment - multi-platform service for full-stack cloud data management (⚠️ NSF funding ended 2024, subscription model Jan 2025)

Open Science Framework (OSF) - free, open platform connecting and supporting the research workflow

WholeTale - NSF-funded platform for creating, sharing, and reproducing computational research

Biomedical & Life Sciences

Galaxy - scientific workflow platform for biomedical research with 500K+ users

KBase - DOE Systems Biology Knowledgebase for predictive biology

Terra.bio - genomics data platform with 80 PB storage and 65K+ users on GCP/Azure

DNAnexus - cloud-based platform for DNA sequence data analysis and management

Gen3 - NIH data commons framework for managing, analyzing, and sharing research data

ELIXIR Compute Platform - European life sciences infrastructure for computational workflows

Geospatial & Earth Science

CyberGIS - NSF-funded HPC and cloud service for geospatial data analyses

Google Earth Engine (GEE) - petabyte-scale platform for Earth science data & analysis

Microsoft Planetary Computer - Azure compute environment with multi-petabyte catalog of Earth observation data (Pro version launched May 2025)

Open Data Cube - open-source platform for Earth observation data with monthly releases

OpenEO Cloud - cloud platform for large-scale Earth observation data processing

PANGEO - community platform for big data geoscience

Copernicus Climate Data Store - European C3S climate toolbox infrastructure

Euro Data Cube - Earth observation data platform for European Sentinel data

Sentinel Hub - satellite imagery platform (acquired by Planet Labs August 2023)

Climate Toolbox - US-focused tool for accessing North America climate data

SciMAAP - NASA/ESA Multi-Mission Algorithm and Analysis Platform

Engineering & Natural Hazards

DesignSafe-CI - comprehensive cyberinfrastructure for natural hazards engineering research

Water Resources

HydroShare - CUAHSI-supported platform for hydrological science applications and data sharing

Materials Science

Materials Cloud - platform for computational materials science with AiiDA provenance tracking

Materials Project - materials database serving 600K+ researchers with pymatgen API

NOMAD - materials database with 19.2M+ entries and AI Toolkit

Ocean & Marine Science

Ocean Observatories Initiative (OOI) - NSF ocean sensor network infrastructure for sustained ocean observations

SeaDataNet - pan-European marine data infrastructure with 110+ data centers

Agriculture

GEMS Informatics Platform - University of Minnesota agri-food data and computational platform

AI & Specialized Computing

NAIRR Pilot - National AI Research Resource pilot launched January 2024 with 150+ resource awards

NDIF (National Deep Inference Facility) - $9M NSF facility for large language model interpretability research

DeltaAI - NCSA's NVIDIA GH200 Grace Hopper system supporting NAIRR/NDIF

ICICLE (Intelligent CyberInfrastructure with Computational Learning in the Environment) - NSF AI Institute with $20M funding through 2026

FutureHouse Platform - AI research agents for scientific discovery (launched May 2024)

Data Transfer & Management Services

Globus - research data management platform serving 170K+ researchers for secure, reliable data transfer

Development Environments & Notebooks

Cloud Development Environments

Google Colab - free Jupyter notebooks with GPU access, AI-first with Gemini integration (September 2025)

GitHub Codespaces - cloud-based VS Code instances from GitHub repositories (120 free core-hours monthly)

MyBinder.org - free reproducible computing environments from GitHub repositories (RStudio, Jupyter, VS Code)

GitPod - automated dev environments in the cloud

Development Tools

Posit - formerly RStudio, rebranded July 2022 for multi-language data science (R, Python, VS Code)

Data Repositories & Infrastructure

Zenodo - CERN-hosted open data repository with 50GB per upload limit

InvenioRDM - repository software powering Zenodo (v13.0 released July 2025)

OpenAIRE - European open science infrastructure with 100M+ publications and datasets

European Research Infrastructure

European Open Science Cloud (EOSC) - EU initiative for federated open science infrastructure and services

EOSC EU Node - first European federation node launched 2024

EGI Federation - European Grid Infrastructure providing advanced computing services for EOSC

EUDAT - European data infrastructure with B2DROP, B2SHARE, B2SAFE services

D4Science - European e-Infrastructure platform for collaborative research

Regional Research Infrastructure

Canada

Compute Canada - national advanced research computing platform (transitioning to Digital Research Alliance)

Digital Research Alliance of Canada - national organization providing research computing, data management, and software services

Federated Research Data Repository (FRDR) - bilingual national data repository for Canadian researchers

Australia & New Zealand

AARNet - Australia's Academic and Research Network providing high-speed connectivity and cloud services

New Zealand eScience Infrastructure (NeSI) - national computing infrastructure for New Zealand researchers

South Africa

National Integrated Cyberinfrastructure System (NICIS) - South Africa's Centre for High Performance Computing (note: nicis.ac.za has SSL issues, using CHPC alternate URL)

Ended or Transitioned Services

⚠️ XSEDE (Extreme Science and Engineering Discovery Environment) - US NSF advanced cyberinfrastructure program ended in 2022, replaced by ACCESS (Advanced Cyberinfrastructure Coordination Ecosystem)

⚠️ National Data Service (NDS) Labs - experimental space for research data management services (inactive since 2018)

⚠️ National Data Service (NDS) Labs - experimental space for research data management services (inactive since 2018)

⚠️ ABoVE (Arctic-Boreal Vulnerability Experiment) - NASA Arctic-Boreal campaign completed May 2025

⚠️ Data8 edX Course - UC Berkeley's data science MOOC on hiatus, but Berkeley course continues

ℹ️ Seven Bridges - merged into Velsera January 2023, Seven Bridges brand continues